PC - Minimumskrav
OS: Windows® XP/Windows Vista®/Windows® 7 (Latest Service Packs) with DirectX® 9.0c
Processor: Intel Pentium® D 2.8 GHz or AMD AthlonTM 64 X2 4400+
Video: NVIDIA® GeForce® 7800 GT or ATI Radeon™ X1950 Pro or better

Mac - Minimumskrav
OS: Mac® OS X 10.6.8, 10.7.X (Latest Version) | Processor: Intel® Core 2 DuoVideo: NVIDIA® GeForce® 8600M GT or ATI Radeon™ HD 2600 or better

All Platforms - Minimumskrav
HD Space: 12 GB available HD space | Memory: 1 GB RAM (1.5 GB required for Windows Vista®/
Windows® 7 users, 2 GB for Mac® users) | Drive: DVD-ROM drive | Internet: Broadband Internet
connection | Display: 1024x768 minimum display resolution

PC - Anbefalet
OS: Windows Vista®/Windows® 7 (Latest Service Packs) | Processor: Intel® Core 2 Duo 2.4 GHz
or AMD AthlonTM 64 X2 5600+ 2.8 GHz | Memory: 2 GB RAM | Video: NVIDIA® GeForce® 260 or
ATI Radeon™ HD 4870 or better

Mac - Anbefalet
OS: Mac® OS X 10.7.X (Latest Version) | Processor: Intel® Core 2 Duo | Memory: 2 GB RAM
Video: NVIDIA® GeForce® GT 330M or ATI Radeon™ HD 4670 or better

Kilden kan findes her http://us.battle.net/support/en/article/diablo-iii-system-requirements